Having worked on more than 30 ecommerce sites, designer Erika Clary has learned a thing or two about what makes a corporate Web site effective. She is now transferring her skills to the nonprofit world, designing Web sites for San Francisco Bay Area nonprofits such as SF Connect, a new organization that mobilizes volunteers.

“Getting buyers to contribute money is really the same thing as selling something online,” she says. Both require well-organized content, a professional appearance, and...

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